1
general::
The beginning and the end, the first and the last, as in She had to master the alpha and omega of the new computer program before she could even begin. This idiom and its meaning, based on the first and last letters of the Greek alphabet, appears in the New Testament (Revelation 1:8): "I am Alpha and Omega, the beginning and the ending, saith the Lord," where it is repeated three more times.
American Heritage Idioms
2
general::
Phrase(s): alpha and omega
both the beginning and the end; the essentials, from the beginning to the end; everything, from the beginning to the end. • He was forced to learn the alpha and omega of corporate law in order to even talk to the lawyers. • He loved her deeply. She was his alpha and omega.
McGrawhill's American Idioms And Phrasal Verbs